Matrix-assisted laser desorption/ionization (MALDI) and electrospray ionization (ESI) mass spectrometry has become an important tool in the life sciences. Recently, mass spectrometry methods have been ...

Mass spectrometry (MS) is already perhaps the most popular analytical chemistry tool in drug discovery and development. Its use is ubiquitous in bioanalytical laboratories for drug and metabolite ...

Electrospray ionization mass spectrometry (ESI-MS) has emerged as a pivotal analytical tool, enabling the gentle conversion of analytes in solution into gas-phase ions while minimising fragmentation.

Osaka, Japan – Tissues consist of a heterogenous mixture of different cell types, complicating our understanding of their biological functions and studies of disease. Now, a multi-institutional team ...

Electrospray ionization (ESI) is best known as a way to introduce chemical compounds and mixtures into mass spectrometers. The machines apply a voltage to a stream of liquid containing a sample, ...

"Tiny 'tornado' boosts performance of electrospray ionization mass spectrometry." ScienceDaily. www.sciencedaily.com / releases / 2017 / 06 / 170629085704.htm (accessed March 22, 2026).

Investigation of leptomeningeal disease in high grade glioma and characterization of molecular alterations. This is an ASCO Meeting Abstract from the 2023 ASCO Annual Meeting I. This abstract does not ...

Genome-wide molecular characterization of mucinous colorectal adenocarcinoma. Background: In this study, desorption electrospray ionization (DESI) mass spectrometry (MS) was used in an imaging mode to ...

What are the ionization techniques for mass spectrometry? Mass spectrometry (MS) plays a vital role in many aspects of our lives, from diagnosing illness and detecting food contaminants to fighting ...

Researchers have developed a novel technology that allows the distribution of components within a single cell to be accurately detected and visualized. Positioning a t-SPESI (tapping-mode scanning ...