For a long time, evolutionary biologists have thought that the genetic mutations that drive the evolution of genes and proteins are largely neutral: they're neither good nor bad, but just ordinary ...

A major evolutionary theory says most genetic changes don’t really matter, but new evidence suggests that’s not true. Researchers found that helpful mutations happen surprisingly often. The twist is ...

Researchers published a new study, “Ongoing chromothripsis underpins osteosarcoma genome complexity and clonal evolution,” in Cell that they say solves the mystery of what drives the genomic ...

Vaccinating birds against bird flu reduces the spread of the disease, but may have unintended consequences. This is the warning of a new paper in the journal Science Advances, which concluded that ...

For decades, the standard explanation for autoimmune diseases like rheumatoid arthritis has rested on two pillars: inherited ...

Factoring out nucleotide-level mutation biases from antibody language models dramatically improves prediction of functional mutation effects while reducing computational cost by orders of magnitude.

Directed evolution is a laboratory method that speeds up protein mutations to help create novel cancer and neurodegenerative disorder therapies. In a new study, scientists detail a method called ...

A new platform for studying mtDNA mutations implicated in human disease could help accelerate treatments for mitochondrial ...