Scientists at St. Jude Children’s Research Hospital studied the Vsx2 super-enhancer and its role in the development of the retina. Their assessment showed the super-enhancer has four distinct regions ...
Scientists using lab-grown retina models have identified how gene changes contribute to ocular coloboma, a rare childhood ...
Over the last decade, experiments addressing thyroid hormone's role in the retina have generated a sizeable body of data. They have also inspired many more questions that will no doubt be tested in ...
The National Institutes of Health grant is for $2.3 million over five years and represents the third funding cycle of one of Mu’s NIH grants through a competitive renewal application. Mu conducts his ...
The finding that a tumor-suppressor protein called Rb is required for proper development of the mouse retina is a major step toward understanding why some children develop the devastating eye cancer ...
Researchers have identified a gene that is crucial for the proper development of photoreceptor cells in the retina. The gene works by regulating microexons, tiny fragments of DNA that play an ...
Scientists at St. Jude Children’s Research Hospital identified distinct functions for regions of a super-enhancer that controls gene expression during retina formation, calling it a ‘modular’ ...
Enhancers are regions of DNA that do not code for proteins, but control how genes are expressed. Super-enhancers are clusters of enhancers that together regulate genes with important roles in cell ...